Tags: Protein.
In molecular biology the HMG-CoA reductase family is a family of enzymes which participate in the mevalonate pathway the metabolic pathway that produces cholesterol and other isoprenoids.There are two distinct classes of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase enzymes: class I consists of eukaryotic and most archaeal enzymes EC 1.1.1.34 while class II consists of prokaryotic enzymes EC 1.1.1.88.Class I HMG-CoA reductases catalyse the NADP-dependent synthesis of mevalonate from 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA).
