Tags: Enzyme.
Histone methyltransferases (HMT) are histone-modifying enzymes (including histone-lysine N-methyltransferase and histone-arginine N-methyltransferase) that catalyze the transfer of one two or three methyl groups to lysine and arginine residues of histone proteins. The attachment of methyl groups occurs predominantly at specific lysine or arginine residues on histones H3 and H4.