Tags: Disease.
Hereditary spherocytosis (also known as Minkowski–Chauffard syndrome) is a genetically-transmitted disorder. It exhibits incomplete penetrance in its expression. It is a form of spherocytosis an auto-hemolytic anemia characterized by the production of red blood cells that are sphere-shaped rather than bi-concave disk shaped (donut-shaped) and therefore more prone to hemolysis.On a blood smear Howell-Jolly bodies may be seen within red blood cells.