Hepatocyte nuclear factors

Tags: Protein.

Hepatocyte nuclear factors (HNFs) are a group of phylogenetically unrelated transcription factors that regulate the transcription of a diverse group of genes into proteins. These proteins include blood clotting factors and in addition enzymes and transporters involved with glucose cholesterol and fatty acid transport and metabolism.

arm

p, q

band

11, 24.3, 12, 13.2, 21, 21.1

chromosome

14, 19, 8, 12, 15, 18, 17, 20

EntrezGene

3170, 3172, 3175, 3169, 3171, 3174, 6927, 6928, 9480

HGNCid

11630, 8139, 5023, 5024, 5026, 5022, 11621, 5021, 8138

locus supplementary data

-q22, -q13, -12q24.3, -17q12, -20q13.1, -21.2, -q13.4, -q21.2, 20p11

OMIM id

142410, 189907, 600281, 600288, 602294, 602295, 604164, 604894, 605966

PDB

1JB6, 1LV2, 1M7W, 2H8R

RefSeq

NM_000458, NM_000545, NM_001030004, NM_004133, NM_004496, NM_004497, NM_004498, NM_004852, NM_021784

symbol

FOXA1, FOXA2, FOXA3, HNF1beta LFB3 MODY5 VHNF1, HNF3A, HNF3B, HNF3G, HNF4A, HNF4G, HNF6 HNF6A, HNF6B OC-2, MODY MODY1 NR2A1 TCF14, MODY3HNF1 LFB1 HNF1A, NR2A2, ONECUT1, ONECUT2, TCF1, TCF2

UniProt

O95948, P20823, P35680, P41235, P55317, P55318, Q14541, Q9UBC0, Q9Y261