Tags: Protein.
Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family of proteins that in humans is encoded by the HBEGF gene. HB-EGF-like growth factor is synthesized as a membrane-anchored mitogenic and chemotactic glycoprotein. An epidermal growth factor produced by monocytes and macrophages due to an affinity for heparin is termed HB-EGF. It has been shown to play a role in wound healing cardiac hypertrophy and heart development and function.