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Hartnup disease (also known as pellagra-like dermatosis and Hartnup disorder) is an autosomal recessive metabolic disorder affecting the absorption of nonpolar amino acids (particularly tryptophan that can be in turn converted into serotonin melatonin and niacin). Niacin is a precursor to nicotinamide a necessary component of NAD+.The causative gene SLC6A19 is located on chromosome 5.

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