Tags: Chemical Compound, Chemical Substance.
Harmine is a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds. It occurs in a number of different plants most notably the Middle Eastern plant harmal or Syrian rue (Peganum harmala) and the South American vine Banisteriopsis caapi (also known as yage or ayahuasca). Harmine reversibly inhibits monoamine oxidase A (MAO-A) an enzyme which breaks down monoamines making it a RIMA. Harmine selectively binds to MAO-A but does not inhibit the variant MAO-B.