Halofuginone is a coccidiostat used in veterinary medicine. It is a synthetic halogenated derivative of febrifugine a natural quinazolinone alkaloid which can be found in the Chinese herb Dichroa febrifuga (Chang Shan). Collgard Biopharmaceuticals is developing halofuginone for the treatment of scleroderma and it has received orphan drug designation from the U.S.
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