Tags: Protein.
In molecular biology the H2TH domain (helix-2turn-helix domain) is a DNA-binding domain found in DNA glycosylase/AP lyase enzymes which are involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Most damage to bases in DNA is repaired by the base excision repair pathway. These enzymes are primarily from bacteria and have both DNA glycosylase activity EC 3.2.2.- and AP lyase activity EC 4.2.99.18.
