Tags: Drug.

GW501516 (also known as GW-501516 GW1516 GSK-516 and Endurobol) is a PPARδ receptor agonist that was previously investigated for drug use by GlaxoSmithKline. The drug was discovered to cause cancer in rats and GlaxoSmithKline has ceased development. It activates the same pathways activated through exercise including PPARδ and AMP-activated protein kinase. It had been investigated as a potential treatment for obesity diabetes dyslipidemia and cardiovascular disease.

Gw501516.svg
ATC prefix
none
CAS number
317318-70-0
ChEBI
73726
IUPAC name
4-[(4-methyl-2-[4-(trifluoromethyl)phenyl]-13-thiazol-5-ylmethyl)sulfanyl]-2-methylphenoxyacetic acid
PubChem
9803963

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