Tags: Protein.
In molecular biology the guanylate-binding protein family is a family of GTPases that is induced by interferon (IFN)-gamma. GTPases induced by IFN-gamma (Interferon-inducible GTPase) are key to the protective immunity against microbial and viral pathogens. These GTPases are classified into three groups: the small 47-KD immunity-related GTPases (IRGs) the Mx proteins (MX1 MX2) and the large 65- to 67-kd GTPases. Guanylate-binding proteins (GBP) fall into the last class.
