Tags: Protein.
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B is an enzyme that in humans is encoded by the GSPT2 gene.GSPT2 is closely related to GSPT1 (MIM 139259) a GTP-binding protein that plays an essential role at the G1- to S-phase transition of the cell cycle in yeast and human cells. GSPT1 is a positive regulator of translational accuracy and in a binary complex with eRF1 (MIM 600285) functions as a polypeptide chain release factor.[supplied by OMIM]