Tags: Chemical Compound, Chemical Substance.
GSK744 (also known as S/GSK1265744) is an investigational new drug under development for the treatment of HIV infection. It is an integrase inhibitor with a carbamoyl pyridone structure similar to dolutegravir. In investigational studies the agent has been packaged into nanoparticles (GSK744LAP) conferring an exceptionally long half-life of 21–50 days following a single dose. In theory this would make possible suppression of HIV with dosing as infrequently as once every three months.
