Tags: Protein.
A growth factor-like domain (GFLD) is a protein domain structurally related to epidermal growth factor which has a high binding affinity for the epidermal growth factor receptor. As structural domains within larger proteins GFLD regions commonly bind calcium ions. A subtype present in the N-terminal region of the amyloid precursor protein is a member of the heparin-binding class of GFLDs and may itself have growth factor function particularly in promoting neuronal development.
