Tags: Protein.

GRB2-related adapter protein is a protein that in humans is encoded by the GRAP gene.This gene encodes a member of the GRB2/Sem5 (C. elegans homolog)/Drk (Drosophila homolog) family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin and facilitates the formation of a stable complex with the BCR-ABL oncoprotein.

Loading...

This page contains content from the copyrighted Wikipedia article "GRAP"; that content is used under the GNU Free Documentation License (GFDL). You may redistribute it, verbatim or modified, providing that you comply with the terms of the GFDL.