Tags: Protein.
Cell surface A33 antigen is a protein that in humans is encoded by the GPA33 gene.The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region a single transmembrane domain and a 62-amino acid intracellular tail.