Tags: Protein.
GoLoco motif is a protein structural motif.In heterotrimeric G-protein signalling cell surface receptors (GPCRs) are coupled to membrane-associated heterotrimers comprising a GTP-hydrolyzing subunit G-alpha and a G-beta/G-gamma dimer. The inactive form contains the alpha subunit bound to GDP and complexes with the beta and gamma subunit. When the ligand is associated to the receptor GDP is displaced from G-alpha and GTP is bound.
