Tags: Chemical Compound, Chemical Substance.

GM6001 also known as galardin or ilomastat is a broad-spectrum matrix metalloproteinase inhibitor.GM6001 is a member of the hydroxamic acid class of reversible metallopeptidase inhibitors. The anionic state of the hydroxamic acid group forms a bidentate complex with the active site zinc.Examples of enzymes that ilomastat inhibit include thermolysin peptide deformylase and anthrax lethal factor endopeptidase (LF) produced by the bacterium Bacillus anthracis.

GM6001.svg
IUPAC name
(2R)-N'-hydroxy-N-[(2S)-3-(5H-indol-3-yl)-1-methylamino-1-oxopropan-2-yl]-2-(2-methylpropyl)butanediamide

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