Tags: Disease.
Glutaric acidemia type 1 (or Glutaric Aciduria GA1 or GAT1) is an inherited disorder in which the body is unable to break down completely the amino acids lysine hydroxylysine and tryptophan. Excessive levels of their intermediate breakdown products (glutaric acid glutaryl-CoA 3-hydroxyglutaric acid glutaconic acid) can accumulate and cause damage to the brain (and also other organs) but particularly the basal ganglia which are regions that help regulate movement.
