Tags: Protein.
Glutaredoxins are small redox enzymes of approximately one hundred amino-acid residues that use glutathione as a cofactor. Glutaredoxins are oxidized by substrates and reduced non-enzymatically by glutathione. In contrast to thioredoxins which are reduced by thioredoxin reductase no oxidoreductase exists that specifically reduces glutaredoxins. Instead glutaredoxins are reduced by the oxidation of glutathione. Oxidized glutathione is then regenerated by glutathione reductase.
