Tags: Protein.
Glis1 (Glis Family Zinc Finger 1) is gene encoding a Krüppel-like protein of the same name whose locus is found on Chromosome 1p32.3. The gene is enriched in unfertilised eggs and embryos at the one cell stage and it can be used to promote direct reprogramming of somatic cells to induced pluripotent stem cells also known as iPS cells. Glis1 is a highly promiscuous transcription factor regulating the expression of numerous genes either positively or negatively.
