Tags: Drug.
Glembatumumab vedotin (also known as CDX-011 and CR011-vcMMAE) is an antibody-drug conjugate (ADC) that targets cancer cells expressing transmembrane glycoprotein NMB (GPNMB).In May 2010 the U.S FDA granted Fast Track designation to CDX-011 for the treatment of advanced refractory or resistant GPNMB-expressing breast cancer.