Tags: Disease.
Glanzmann’s thrombasthenia is an abnormality of platelets. It is an extremely rare coagulopathy (bleeding disorder due to a blood abnormality) in which the platelets contain defective or low levels of glycoprotein IIb/IIIa (GpIIb/IIIa) which is a receptor for fibrinogen. As a result no fibrinogen bridging of platelets to other platelets can occur and the bleeding time is significantly prolonged.