Tags: Protein.
Glutamate–cysteine ligase regulatory subunit is an enzyme that in humans is encoded by the GCLM gene.Glutamate-cysteine ligase also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.