Tags: Chemical Compound, Chemical Substance.
GBR-13098 is a psychostimulant and selective dopamine uptake inhibitor.Blocking the endogenous striatal dopamine (DA) transporter with GBR-13098 in mice has been shown to prevented damage to the DA nerve terminals caused by malonate. It was suggested that DA transpoter inhibitors like GBR-13098 could be used to prevent or treat neruodegenerative disorders caused by the effect of mitochondrial dysfunction on DA homeostasis.
