Tags: Protein.
Frizzled-8 is a protein that in humans is encoded by the FZD8 gene.This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines indicating that it may play a role in several types of cancer.