Tags: Chemical Compound, Chemical Substance.
Fura-2-acetoxymethyl ester often abbreviated Fura-2AM is a membrane-permeable derivative of the ratiometric calcium indicator Fura-2 used in biochemistry to measure cellular calcium concentrations by fluorescence. When added to cells Fura-2AM crosses cell membranes and once inside the cell the acetoxymethyl groups are removed by cellular esterases. Removal of the acetoxymethyl esters regenerates Fura-2 the pentacarboxylate calcium indicator.