Tags: Disease.
Froin’s syndrome – coexistence of xanthochromia high protein level and marked coagulation of cerebrospinal fluid (CSF). It is caused by meningeal irritation (e.g. during spinal meningitis) and CSF flow blockage by tumour mass or abscess. Stagnation of the CSF within the thecal sac facilitates exudation from the tumour itself and activation of coagulation factors. Clinical test formerly used for evaluation of spinal stenosis was Queckenstedt’s maneuver.
