Tags: Protein.
In molecular biology formylglycine-generating sulfatase enzyme is a protein domain which has a structure homologous to the complex alpha/beta topology found in sulfatase-modifying factors (SUMF1). SUMF1 is a paralogue of oxoalanine-generating enzyme also called C(alpha)-formylglycine generating enzyme (FGE). SUMF1 converts newly synthesized inactive sulfatases to their active form by modifying an active site cysteine residue to oxoalanine.
