Tags: Protein.
In molecula biology the focal adhesion targeting region is a conserved domain found on focal adhesion kinases.Focal adhesion kinases (FAK) are tyrosine kinases found in focal adhesions intracellular signalling complexes that are formed following engagement of the extracellular matrix by integrins. The C-terminal focal adhesion targeting (FAT) region is necessary and sufficient for localizing FAK to focal adhesions.