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Fluocinolone acetonide is a corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching. It is a synthetic hydrocortisone derivative. The fluorine substitution at position 9 in the steroid nucleus greatly enhances its activity. A typical dosage strength used in dermatology is 0.01โ€“0.025%. One such cream is sold under the brand name Flucort-N and includes the antibiotic neomycin.Flucinolone is a group IV corticosteroid under US classification.

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