Tags: Anatomical Structure.
Glisson’s capsule or Glisson’s sheath is a collagenous capsule covering the external surface of the liver. It consists of type III collagen and extends to the stroma of endothelial sinusoids. Right upper abdominal discomfort (location of liver) occurs in many liver diseases and this pain arises from stretching or irritation of Glisson’s capsule which is rich in nerve endings. It is covered by a single layer of mesothelial cells.