Tags: Protein.
Fasciculation and elongation protein zeta-1 is a protein that in humans is encoded by the FEZ1 gene.This gene is an ortholog of the C. elegans unc-76 gene which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic.