Tags: Protein.
Fas-activated serine/threonine kinase is an enzyme that in humans is encoded by the FASTK gene.The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation it phosphorylates TIA1 an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis.