Tags: Anatomical Structure, Brain.
The fascia dentata is the earliest stage of the hippocampal circuit. Its primary input is the perforant path from the superficial layers of entorhinal cortex. Its principal neurons are tiny granule cells which give rise to unmyelinated axons called the mossy fibers which project to the hilus and CA3. The fascia dentata of the rat contains approximately 1000000 granule cells. It receives feedback connections from mossy cells in the hilus at distant levels in the septal and temporal directions.