Tags: Disease.
Familial adenomatous polyposis (FAP) is an inherited condition in which numerous adenomatous polyps form mainly in the epithelium of the large intestine. While these polyps start out benign malignant transformation into colon cancer occurs when left untreated. Three variants are known to exist FAP and attenuated FAP (originally called “hereditary flat adenoma syndrome) are caused by APC gene defects and autosomal recessive FAP (or MYH-associated polyposis) is caused by MUTYH gene defects.
