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Ethisterone is a progestogen hormone.The first orally active progestin ethisterone (pregneninolone 17α-ethynyltestosterone or 19–norandrostane) the 17α-ethynyl analog of testosterone was synthesized in 1938 by Hans Herloff Inhoffen Willy Logemann Walter Hohlweg and Arthur Serini at Schering AG in Berlin and marketed in Germany in 1939 as Proluton C and by Schering in the U.S. in 1945 as Pranone. Ethisterone was also marketed in the U.S.

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