Tags: Chemical Compound, Chemical Substance.
Eschenmoser’s salt dimethylmethylideneammonium iodide is a strong dimethylaminomethylating agent used to prepare derivatives of the type RCH2N(CH3)2. Enolates enolsilylethers and even more acidic ketones undergo efficient dimethylaminomethylation. Once prepared such tertiary amines can be further methylated and then subjected to base-induced elimination to afford methylenated ketones. The salt was first prepared by the group of Albert Eschenmoser after whom the reagent is named.
