Tags: Protein.
ESAT-6 the 6 kDa early secretory antigenic target of Mycobacterium tuberculosis is a secretory protein and potent T cell antigen. It is used in tuberculosis diagnosis by the whole blood interferon γ test QuantiFERON-TB Gold in conjunction with CFP-10 and TB7.7.ESAT-6 has been shown to directly bind to the TLR2 receptor inhibiting downstream signal transduction.