Tags: Protein.
The epithelial sodium channel (short: ENaC also: sodium channel non-neuronal 1 (SCNN1) or amiloride-sensitive sodium channel (ASSC)) is a membrane-bound ion-channel that is permeable for Li+-ions protons and especially Na+-ions. It is a constitutively active ion-channel. It can be argued that it is the most selective ion channel.The apical membrane of many tight epithelia contains sodium channels that are characterised primarily by their high affinity to the diuretic blocker amiloride.