EGIS-12233 is a drug with applications in scientific research acting as a potent and selective antagonist for both the 5-HT6 and 5-HT7 serotonin receptor subtypes with good selectivity over other receptors. It has been shown to increase dopamine release in cochlear tissue suggesting a role for the 5-HT6 and 5-HT7 receptors in regulation of the hearing system.
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