Tags: Drug.
Edrecolomab (MAb17-1A trade name Panorex) is a mouse-derived monoclonal antibody targeting the cell-surface glycoprotein EpCAM (17-1A) which is expressed on epithelial tissues and on various carcinomas.Preliminary studies had shown promise of a possible use in patients with stage III colorectal carcinoma (with metastasis to the lymph nodes). However when put to a phase III study (2761 patients) it did not provide any benefit when compared to conventional chemotherapeutic agents.