Tags: Drug.
E-55888 is a drug developed by Esteve which acts as a potent and selective full agonist at the 5HT7 serotonin receptor and is used for investigating the role of 5-HT7 receptors in the perception of pain. When administered by itself E-55888 is anti-hyperalgesic but not analgesic but when administered alongside morphine E-55888 was found to significantly increase the analgesic effects.