Tags: Chemical Compound, Chemical Substance.
DSS (44-dimethyl-4-silapentane-1-sulfonic acid) is a chemical compound used in proton- and carbon-related NMR spectroscopy as a calibration standard similar to tetramethylsilane (TMS) but with much higher water solubility. Whereas TMS is the most common NMR standard used in organic solvents such as chloroform or benzene DSS or its sodium salt is more often used for protein experiments in water.The low electronegativity of the silicon shields the nine identical methyl protons.
