Tags: Protein.
In molecular biology the DSS1/SEM1 protein family is a family of short acidic proteins which includes the 26S proteasome complex subunits SEM1 from Saccharomyces cerevisiae and Drosophila and DSS1 (SHFM1) in mammals. In Saccharomyces cerevisiae SEM1 is a regulator of both exocyst function and pseudohyphal differentiation. Loss of DSS1 in Homo sapiens (human) has been associated with split hand/split foot malformations.
