Tags: Disease.
Drusen (singular druse) are tiny yellow or white accumulations of extracellular material that build up between Bruch’s membrane and the retinal pigment epithelium of the eye. The presence of a few small (hard) drusen is normal with advancing age and most people over 40 have some hard drusen. However the presence of larger and more numerous drusen in the macula is a common early sign of age-related macular degeneration (AMD).
