Tags: Protein.
Dihydropyrimidinase is an enzyme that in humans is encoded by the DPYS gene.Dihydropyrimidinase catalyzes the conversion of 56-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.