Tags: Protein.
Dock3 (Dedicator of cytokinesis 3) also known as MOCA (modifier of cell adhesion) and PBP (presenilin-binding protein) is a large (~180 kDa) protein involved in intracellular signalling networks. It is a member of the DOCK-B subfamily of the DOCK family of guanine nucleotide exchange factors (GEFs) which function as activators of small G proteins. Dock3 specifically activates the small G protein Rac.