Tags: Protein.
DNA glycosylases are a family of enzymes involved in base excision repair classified under EC number EC 3.2.2. Base excision repair is the mechanism by which damaged bases in DNA are removed and replaced. DNA glycosylases catalyze the first step of this process. They remove the damaged nitrogenous base while leaving the sugar-phosphate backbone intact creating an apurinic/apyrimidinic site commonly referred to as an AP site.