Tags: Chemical Compound, Chemical Substance.

Dithiothreitol (DTT) is the common name for a small-molecule redox reagent known as Cleland’s reagent. DTT’s formula is C4H10O2S2 and the molecular structure of its reduced form is shown at the right; its oxidized form is a disulfide-bonded 6-membered ring (shown below). Its name derives from the four-carbon sugar threose. DTT has an epimeric (‘sister’) compound dithioerythritol (DTE).

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